Achievements研究成果

2025年

  1. H2A.Z reinforces maternal H3K4me3 formation and is essential for meiotic progression in mouse oocytes
    Mei H, Hayashi R, Kozuka C, Kumon M, Koseki H, Inoue A.
    Nat Struct Mol Biol. 2025 June 13. doi.org/10.1038/s41594-025-01573-x
    論文紹介
     
  2. An ex vivo uterine system captures implantation, embryogenesis, and trophoblast invasion via maternal-embryonic signaling
    Hiraoka T, Aikawa S, Mashiko D, Nakagawa T, Shirai H, Hirota Y, Kimura H, Ikawa M.
    Nat Commun. 2025 Jul 1;16:5755. doi: 10.1038/s41467-025-60610-x
    論文紹介
     

  3. Proximity labeling of axonemal protein CFAP91 identifies EFCAB5 that regulates sperm motility. 
    Wang H, Shimada K, Pham AH, Oyama Y, Kamoshita M, Kobayashi H, Oura S, Yabuta N, Ikawa M, Miyata H.
    Nat Commun. 2025 Sep 10;16(1):8238. doi: 10.1038/s41467-025-63705-7.

  4. GALNTL5 binds GalNAc and is required for migration through the uterotubal junction and sperm-zona pellucida binding.
    Noda T, Uriu R, Mashiko D, Shinohara H, Qu Y, Taira A, Matzuk RM, Tahala D, Nakano M, Araki K, Yu Z, Zhang Y, Matzuk MM, Ikawa M.
    Nat Commun. 2025 Sep 17;16(1):8264. doi: 10.1038/s41467-025-63805-4.

  5. In vitro system completely restores oogenesis in congenitally infertile mice.
    Yoshida K, Kimura S, Taguchi M, Morimoto H, Kanatsu-Shinohara M, Shinohara T, Obata Y.
    Hum Reprod. 2025 Oct 7; doi:10.1093/humrep/deaf194.
     

  6. Sperm and offspring production in a nonobstructive azoospermia mouse model via testicular mRNA delivery using lipid nanoparticles
    Mashiko D, Emori C, Hatanaka Y, Motooka D, Pan C, Kaneda Y, Matzuk MM, Ikawa M.
    Proc Natl Acad Sci U S A. 2025 Oct 21;122(42):e2516573122.
    doi: 10.1073/pnas.2516573122. PMID: 41082659
    論文紹介

  7. Formation of a complex between TMEM217 and the sodium-proton exchanger SLC9C1 is crucial for mouse sperm motility and male fertility
    Iida-Norita R, Miyata H, Ninomiya A, Emori C, Kamoshita M, Pan C, Wang H, Ikawa M.
    Proc Natl Acad Sci U S A. 2025 Oct 21;122(42):e2513924122.
    doi: 10.1073/pnas.2513924122. PMID: 41091759

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